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DISEASE WITH SPECIFIC CLINICAL MANIFESTATION

Here are the comprehensive and most commonly used sign and symptom that indicates particular disease 

ACROMEGALY-Coarse facial feature
ADDISON’S DISEASE bronze like skin pigmentation
ANGINA Crushing stubbing pain relieved by NTG
APPENDICITIS rebound tenderness
ASTHMA wheezing on expiration
BLADDER CA painless hematuria
BPH reduced size & force of urine
BULIMIA chipmunk face
CATARACT Painless vision loss, Opacity of the lens, blurring of vision
CHICKEN POX Vesicular Rash (central to distal) dew drop on rose petal
CHOLERA rice watery stool
CUSHING’S SYNDROME moon face appearance and buffalo hump.
CYSTIC FIBROSIS Salty skin
CYSTITIS burning on urination
DENGUE petechiae or (+) Herman’s sign.
DIPTHERIA pseudo membrane formation
DKA Kussmauls breathing (Deep Rapid RR)
DM polyuria, polydypsia, polyphagia
DOWN SYNDROME
protruding tongue
DUCHENNE’S MUSCULAR DYSTROPHY Gowers’ sign (use of hands to push one’s self from the floor)
DVT Homan’s Sign
EMPHYSEMA barrel chest
EPIGLOTITIS 3Ds’ Drooling, Dysphonia, Dysphagia
FIBRIN HYALIN Expiratory Grunt
GERD Barretts esophagus (erosion of the lower portion of the esophageal mucosa)
GLAUCOMA Painfull vision loss, tunnel/gun barrel/halo vision (Peripheral Vision Loss)
Guillain Barre Syndrome ascending muscle weakness
HEPATIC ENCEPHALOPATHY Flapping tremors
HODGKIN’S DISEASE/LYMPHOMA painless, progressive enlargement of spleen & lymph tissues, Reedstenberg Cells
HYDROCEPHALUS Bossing sign (prominent forehead)
HYPERTHYROIDISM/GRAVE’S DISEASE exopthalmus
HYPOCALCEMIA Chvostek & Trosseaus sign
INCREASE ICP HYPERtension BRADYpnea BRADYcardia (Cushing’s Triad)
INFECTIOUS MONONUCLEOSIS Hallmark: sore throat, cervical lymph adenopathy, fever
INTUSSUSCEPTION sausage shaped mass, Dance Sign (empty portion of RLQ)
KAWASAKI SYNDROME strawberry tongue
LEPROSY lioning face
LIVER CIRRSIS spider like varices
LTB inspiratory stridor
LYME’S DISEASE Bull’s eye rash
MALARIA stepladder like fever with chills
MEASLES koplik’s spots.
MENINGITIS Kernig’s sign (leg flex then leg pain on extension), Brudzinski sign (neck flex = lower leg flex).
MG descending muscle weakness (assending weak muscle in GBS)
 MI Crushing stubbing pain which radiates to left shoulder, neck, arms, unrelieved by NTG
MS Charcot’s Triad (IAN)
PANCREATITIS Cullen’s sign (ecchymosis of umbilicus); (+) Grey turners spots.
PARKINSON’S DISEASE Pill-rolling tremors
PDA machine like murmur
PEMPHIGUS VULGARIS Nikolsky’s sign (separation of epidermis caused by rubbing of the skin)
PERNICIOUS ANEMIA red beefy tongue
PNEUMONIA rusty sputum
PTB low-grade afternoon fever
PYLORIC STENOSIS olive like mass
RETINAL DETACHMENT Visual Floaters, flashes of light, curtain vision
RETINO BLASTOMA Cat’s eye reflex (grayish discoloration of pupils)
SHOCK HYPOtension TACHYpnea TACHYcardia
SLE butterfly rashes
TEF 4Cs’ Coughing, Choking, Cyanosis, Continorooling
TETANUS risus sardonicus.
TETANY hypocalcemia (+) Trousseau’s sign/carpopedal spasm; Chvostek sign (facial spasm)
TYPHOID rose spots in abdomen.
ULCERATIVE COLITIS recurrent bloody diarrhea

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